AKAP13

AKAP13
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2DRN, 2LG1, 4D0N, 4D0O
Identifiers
Aliases	AKAP13, A kinase (PRKA) anchor protein 13, AKAP-13, AKAP-Lbc, ARHGEF13, BRX, HA-3, Ht31, LBC, PRKA13, PROTO-LB, PROTO-LBC, c-lbc, p47, A-kinase anchoring protein 13, A-kinase anchor protein 13
External IDs	MGI: 2676556 HomoloGene: 4903 GeneCards: AKAP13
Gene ontology Molecular function • metal ion binding • MAP-kinase scaffold activity • Rho guanyl-nucleotide exchange factor activity • guanyl-nucleotide exchange factor activity • protein binding • protein complex scaffold activity • protein kinase A binding • Rho GTPase binding • signal transducer activity • cAMP-dependent protein kinase activity Cellular component • membrane • cytosol • actin cytoskeleton • perinuclear region of cytoplasm • nucleus • cell cortex • actin filament • cortical actin cytoskeleton • cytoplasm • intracellular Biological process • positive regulation of GTPase activity • regulation of cardiac muscle hypertrophy • bone development • intracellular signal transduction • regulation of glucocorticoid mediated signaling pathway • positive regulation of Rho protein signal transduction • activation of MAPK activity by adrenergic receptor signaling pathway • regulation of sarcomere organization • positive regulation of I-kappaB kinase/NF-kappaB signaling • G-protein coupled receptor signaling pathway • adrenergic receptor signaling pathway • regulation of small GTPase mediated signal transduction • adrenergic receptor signaling pathway involved in heart process • heart development • positive regulation of apoptotic process • cardiac muscle cell differentiation • regulation of Rho protein signal transduction • protein phosphorylation • regulation of protein kinase activity • nuclear export Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	11214	75547
Ensembl	ENSG00000170776	ENSMUSG00000066406
UniProt	Q12802	E9Q394
RefSeq (mRNA)	NM_144767 NM_001270546 NM_006738 NM_007200	NM_029332
RefSeq (protein)	NP_001257475 NP_006729 NP_009131	NP_083608
Location (UCSC)	Chr 15: 85.38 – 85.75 Mb	Chr 7: 75.46 – 75.75 Mb
PubMed search

2DRN, 2LG1, 4D0N, 4D0O

11214

75547

ENSG00000170776

ENSMUSG00000066406

Q12802

E9Q394

NM_144767
NM_001270546
NM_006738
NM_007200

NM_029332

NP_001257475
NP_006729
NP_009131

NP_083608

A-kinase anchor protein 13 is an enzyme that in humans is encoded by the AKAP13 gene.

...
Wikipedia