ADCYAP1R1

ADCYAP1R1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 2JOD
Identifiers
Aliases	ADCYAP1R1, PAC1, PAC1R, PACAPR, PACAPRI, ADCYAP receptor type I
External IDs	MGI: 108449 HomoloGene: 870 GeneCards: ADCYAP1R1
Gene ontology Molecular function • G-protein coupled receptor activity • adenylate cyclase binding • neuropeptide binding • vasoactive intestinal polypeptide receptor activity • signal transducer activity • protein binding • ADP-ribosylation factor binding • transmembrane signaling receptor activity • receptor activity Cellular component • cytoplasm • integral component of membrane • endosome • rough endoplasmic reticulum • membrane • bicellular tight junction • receptor complex • plasma membrane • integral component of plasma membrane • cell surface • caveola • neuron projection Biological process • positive regulation of cAMP biosynthetic process • G-protein coupled receptor signaling pathway • cell differentiation • multicellular organismal response to stress • response to estradiol • positive regulation of calcium ion transport into cytosol • positive regulation of inositol phosphate biosynthetic process • negative regulation of cell death • activation of phospholipase C activity • multicellular organism development • cell surface receptor signaling pathway • development of primary female sexual characteristics • spermatogenesis • response to ethanol • cAMP-mediated signaling • response to drug • signal transduction • positive regulation of small GTPase mediated signal transduction Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	117	11517
Ensembl	ENSG00000078549	ENSMUSG00000029778
UniProt	P41586	P70205
RefSeq (mRNA)	NM_001118 NM_001199635 NM_001199636 NM_001199637	NM_001025372 NM_007407
RefSeq (protein)	NP_001109 NP_001186564 NP_001186565 NP_001186566	NP_031433.3 NP_001020543 NP_031433
Location (UCSC)	Chr 7: 31.05 – 31.11 Mb	Chr 6: 55.45 – 55.5 Mb
PubMed search

2JOD

117

11517

ENSG00000078549

ENSMUSG00000029778

P41586

P70205

NM_001118
NM_001199635
NM_001199636
NM_001199637

NM_001025372
NM_007407

NP_001109
NP_001186564
NP_001186565
NP_001186566

NP_031433.3
NP_001020543
NP_031433

Pituitary adenylate cyclase-activating polypeptide type I receptor also known as PAC₁, is a protein that in humans is encoded by the ADCYAP1R1 gene. This receptor binds pituitary adenylate cyclase activating peptide.

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