ADAMTSL1

ADAMTSL1
Identifiers
Aliases	ADAMTSL1, ADAMTSL-1, ADAMTSR1, C9orf94, PUNCTIN, ADAMTS like 1
External IDs	MGI: 1924989 HomoloGene: 64642 GeneCards: ADAMTSL1
Gene location (Human) Chr. Chromosome 9 (human) Band 9p22.2-p22.1 Start 17,906,563 bp End 18,910,950 bp
Gene location (Mouse) Chr. Chromosome 4 (mouse) Band 4|4 C4 Start 85,514,172 bp End 86,428,385 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • zinc ion binding • peptidase activity • hydrolase activity • metalloendopeptidase activity Cellular component • proteinaceous extracellular matrix • extracellular region • endoplasmic reticulum lumen Biological process • protein O-linked fucosylation • proteolysis Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	92949	77739
Ensembl	ENSG00000178031	ENSMUSG00000066113
UniProt	Q8N6G6	Q8BLI0
RefSeq (mRNA)	NM_001040272 NM_052866 NM_139238 NM_139264	NM_029967 NM_172542
RefSeq (protein)	NP_001035362 NP_443098	NP_084243
Location (UCSC)	Chr 9: 17.91 – 18.91 Mb	Chr 9: 85.51 – 86.43 Mb
PubMed search

92949

77739

ENSG00000178031

ENSMUSG00000066113

Q8N6G6

Q8BLI0

NM_001040272
NM_052866
NM_139238
NM_139264

NM_029967
NM_172542

NP_001035362
NP_443098

NP_084243

ADAMTS-like protein 1 is a protein that in humans is encoded by the ADAMTSL1 gene.

This gene encodes a secreted protein resembling members of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) family. This protein lacks the propeptide region and the metalloproteinase and disintegrin-like domains, which are typical of the ADAMTS family, but contains other ADAMTS domains, including the thrombospondin type 1 motif. This protein may have important functions in the extracellular matrix. Alternatively spliced transcript variants have been described, but their biological validity has not been determined.

...
Wikipedia