ACTH receptor

MC2R
Identifiers
Aliases	MC2R, ACTHR, melanocortin 2 receptor
External IDs	OMIM: 607397 MGI: 96928 HomoloGene: 444 GeneCards: MC2R
Gene ontology Molecular function • melanocortin receptor activity • protein binding • G-protein coupled receptor activity • corticotropin receptor activity • signal transducer activity Cellular component • cytoplasm • integral component of membrane • plasma membrane • integral component of plasma membrane • membrane Biological process • positive regulation of cAMP biosynthetic process • G-protein coupled receptor signaling pathway • G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger • signal transduction • placenta development • neuropeptide signaling pathway Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	4158	17200
Ensembl	ENSG00000185231	ENSMUSG00000045569
UniProt	Q01718	Q64326
RefSeq (mRNA)	NM_001291911 NM_000529	NM_001271716 NM_001271717 NM_008560 NM_001301372
RefSeq (protein)	NP_000520 NP_001278840	NP_001258645.1 NP_001258646.1 NP_001288301.1 NP_032586.1 NP_001258645 NP_001258646 NP_001288301 NP_032586
Location (UCSC)	Chr 18: 13.88 – 13.92 Mb	Chr 18: 68.41 – 68.43 Mb
PubMed search

4158

17200

ENSG00000185231

ENSMUSG00000045569

Q01718

Q64326

NM_001291911
NM_000529

NM_001271716
NM_001271717
NM_008560
NM_001301372

NP_000520
NP_001278840

NP_001258646
NP_001288301
NP_032586

The adrenocorticotropic hormone receptor or ACTH receptor also known as the melanocortin receptor 2 or MC₂ receptor is a type of melanocortin receptor (type 2) which is specific for ACTH. It is a G-coupled receptor located on the external cell plasma membrane, and plays a role in immune function and glucose metabolism.

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Wikipedia