ACAT1

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
2F2S, 2IB7, 2IB8, 2IB9, 2IBU, 2IBW, 2IBY

Identifiers

Aliases

ACAT1, ACAT, MAT, T2, THIL, acetyl-CoA acetyltransferase 1

External IDs

OMIM: 607809 MGI: 87870 HomoloGene: 6 GeneCards: ACAT1

Gene ontology
Molecular function	• transferase activity • protein homodimerization activity • transferase activity, transferring acyl groups other than amino-acyl groups • metal ion binding • catalytic activity • coenzyme binding • enzyme binding • transferase activity, transferring acyl groups • carbon-carbon lyase activity • ligase activity, forming carbon-carbon bonds • acetyl-CoA C-acetyltransferase activity
Cellular component	• mitochondrial matrix • mitochondrial inner membrane • extracellular exosome • mitochondrion
Biological process	• response to organic cyclic compound • branched-chain amino acid catabolic process • metanephric proximal convoluted tubule development • ketone body biosynthetic process • brain development • response to starvation • response to hormone • liver development • adipose tissue development • metabolic process • protein homooligomerization • acetyl-CoA catabolic process • coenzyme A metabolic process • fatty acid beta-oxidation • coenzyme A biosynthetic process • acetyl-CoA biosynthetic process • ketone body catabolic process • isoleucine catabolic process • propionyl-CoA biosynthetic process • ketone body metabolic process
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


38


110446

Ensembl


ENSG00000075239


ENSMUSG00000032047

UniProt


P24752


Q8QZT1

RefSeq (mRNA)


NM_000019


NM_144784

RefSeq (protein)


NP_000010


NP_659033.1 NP_659033

Location (UCSC)

Chr 11: 108.12 – 108.15 Mb

Chr 9: 53.58 – 53.61 Mb

PubMed search

2F2S, 2IB7, 2IB8, 2IB9, 2IBU, 2IBW, 2IBY

NP_659033.1
NP_659033

Acetyl-CoA acetyltransferase, mitochondrial, also known as acetoacetyl-CoA thiolase, is an enzyme that in humans is encoded by the ACAT1 (Acetyl-Coenzyme A acetyltransferase 1) gene.

Acetyl-Coenzyme A acetyltransferase 1 is an acetyl-CoA C-acetyltransferase enzyme.

...
Wikipedia