ABHD6

ABHD6
Identifiers
Aliases	ABHD6, abhydrolase domain containing 6
External IDs	MGI: 1913332 HomoloGene: 23246 GeneCards: ABHD6
Gene location (Human) Chr. Chromosome 3 (human) Band 3p14.3 Start 58,237,506 bp End 58,295,693 bp
Gene location (Mouse) Chr. Chromosome 14 (mouse) Band 14|14 A1 Start 8,002,902 bp End 8,056,555 bp
Gene ontology Molecular function • catalytic activity • hydrolase activity • acylglycerol lipase activity • phospholipase activity Cellular component • integral component of membrane • plasma membrane • AMPA glutamate receptor complex • extracellular exosome • membrane • mitochondrion Biological process • acylglycerol catabolic process • negative regulation of cell migration • positive regulation of lipid biosynthetic process • regulation of endocannabinoid signaling pathway • phospholipid catabolic process • long term synaptic depression Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	57406	66082
Ensembl	ENSG00000163686	ENSMUSG00000025277
UniProt	Q9BV23	Q8R2Y0
RefSeq (mRNA)	NM_020676 NM_001320126	NM_025341 NM_001331064 NM_001331065
RefSeq (protein)	NP_001307055 NP_065727 NP_065727.4 NP_001307055.1	NP_001317993 NP_001317994 NP_079617
Location (UCSC)	Chr 3: 58.24 – 58.3 Mb	Chr 3: 8 – 8.06 Mb
PubMed search

57406

66082

ENSG00000163686

ENSMUSG00000025277

Q9BV23

Q8R2Y0

NM_020676
NM_001320126

NM_025341
NM_001331064
NM_001331065

NP_001307055
NP_065727
NP_065727.4
NP_001307055.1

NP_001317993
NP_001317994
NP_079617

alpha/beta-Hydrolase domain containing 6 (ABHD6), also known as monoacylglycerol lipase ABHD6 or 2-arachidonoylglycerol hydrolase is an enzyme that in humans is encoded by the ABHD6 gene.

ABHD6 is a serine hydrolyzing enzyme that possesses typical α/β-hydrolase family domains. ABHD6 was first studied because of its over-expression in certain forms of tumours.

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Wikipedia