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ABCG1

ABCG1
Identifiers
Aliases ABCG1, ABC8, WHITE1, ATP binding cassette subfamily G member 1
External IDs MGI: 107704 HomoloGene: 21022 GeneCards: ABCG1
Genetically Related Diseases
amyotrophic lateral sclerosis
RNA expression pattern
PBB GE ABCG1 204567 s at tn.png

PBB GE ABCG1 211113 s at tn.png
More reference expression data
Orthologs
Species Human Mouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_009593

RefSeq (protein)

NP_033723.1

Location (UCSC) Chr 21: 42.2 – 42.3 Mb Chr 17: 31.06 – 31.12 Mb
PubMed search

NM_207629
NM_207630

NM_009593

NP_997512

NP_033723.1

ATP-binding cassette sub-family G member 1 is a protein that in humans is encoded by the ABCG1 gene. It is a homolog of the well-known Drosophila gene white.

The protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the White subfamily. It is involved in macrophage, cholesterol and phospholipids transport, and may regulate cellular lipid homeostasis in other cell types. Several alternative splice variants have been identified.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


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