ABCC12

ABCC12
Identifiers
Aliases	ABCC12, MRP9, ATP binding cassette subfamily C member 12
External IDs	MGI: 2441679 HomoloGene: 57211 GeneCards: ABCC12
Gene location (Human) Chr. Chromosome 16 (human) Band 16q12.1 Start 48,082,973 bp End 48,156,018 bp
Gene location (Mouse) Chr. Chromosome 8 (mouse) Band n/a Start 86,482,260 bp End 86,580,686 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • ATPase activity • ATP binding • ATPase activity, coupled to transmembrane movement of substances Cellular component • integral component of membrane • mitochondrion • membrane Biological process • transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	94160	244562
Ensembl	ENSG00000140798	ENSMUSG00000036872
UniProt	Q96J65	Q80WJ6
RefSeq (mRNA)	NM_145190 NM_033226 NM_145187 NM_145188 NM_145189	NM_172912
RefSeq (protein)	NP_150229	NP_766500
Location (UCSC)	Chr 16: 48.08 – 48.16 Mb	Chr 16: 86.48 – 86.58 Mb
PubMed search

94160

244562

ENSG00000140798

ENSMUSG00000036872

Q96J65

Q80WJ6

NM_145190
NM_033226
NM_145187
NM_145188
NM_145189

NM_172912

NP_150229

NP_766500

Multidrug resistance-associated protein 9 is a protein that in humans is encoded by the ABCC12 gene.

This gene is a member of the superfamily of ATP-binding cassette (ABC) transporters and the encoded protein contains two ATP-binding domains and 12 transmembrane regions. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies: ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White. This gene is a member of the MRP subfamily which is involved in multi-drug resistance. This gene and another subfamily member are arranged head-to-tail on chromosome 16q12.1. Increased expression of this gene is associated with breast cancer.

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Wikipedia