ABCB9

ABCB9
Identifiers
Aliases	ABCB9, EST122234, TAPL, ATP binding cassette subfamily B member 9
External IDs	MGI: 1861729 HomoloGene: 10491 GeneCards: ABCB9
Gene location (Human) Chr. Chromosome 12 (human) Band 12q24.31 Start 122,920,951 bp End 122,981,649 bp
Gene location (Mouse) Chr. Chromosome 5 (mouse) Band n/a Start 124,061,530 bp End 124,095,798 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • nucleotide binding • ATPase activity • protein homodimerization activity • substrate-specific transmembrane transporter activity • oligopeptide-transporting ATPase activity • ATP binding • peptide-transporting ATPase activity • ATPase activity, coupled to transmembrane movement of substances • protein binding Cellular component • integral component of membrane • early endosome • membrane • integral component of endoplasmic reticulum membrane • endoplasmic reticulum • lysosome • lysosomal membrane • intracellular membrane-bounded organelle Biological process • transmembrane transport • peptide transport • antigen processing and presentation of peptide antigen via MHC class I • protein transport • oligopeptide transmembrane transport • transport Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	23457	56325
Ensembl	ENSG00000150967	ENSMUSG00000029408
UniProt	Q9NP78	Q9JJ59
RefSeq (mRNA)	NM_001243013 NM_001243014 NM_019624 NM_019625 NM_203444 NM_203445	NM_019875
RefSeq (protein)	NP_001229942 NP_001229943 NP_062570 NP_062571 NP_982269	NP_063928
Location (UCSC)	Chr 12: 122.92 – 122.98 Mb	Chr 12: 124.06 – 124.1 Mb
PubMed search

23457

56325

ENSG00000150967

ENSMUSG00000029408

Q9NP78

Q9JJ59

NM_203445

NM_019875

NP_001229942
NP_001229943
NP_062570
NP_062571
NP_982269

NP_063928

ATP-binding cassette sub-family B member 9 is a protein that in humans is encoded by the ABCB9 gene.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. The function of this half-transporter has not yet been determined; however, this protein may play a role in lysosomes. Alternative splicing of this gene results in distinct isoforms which are likely to have different substrate specifications.

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Wikipedia