ABCB7

ABCB7
Identifiers
Aliases	ABCB7, AA517758, AU019072, Abc7, ASAT, Atm1p, EST140535, ATP binding cassette subfamily B member 7
External IDs	MGI: 109533 HomoloGene: 3175 GeneCards: ABCB7
Gene ontology Molecular function • nucleotide binding • heme transporter activity • ATPase activity • ATPase activity, coupled to transmembrane movement of substances • ATP binding Cellular component • membrane • mitochondrial inner membrane • mitochondrion • integral component of membrane Biological process • transmembrane transport • cellular iron ion homeostasis • heme transport • transport Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	22	11306
Ensembl	ENSG00000131269	ENSMUSG00000031333
UniProt	O75027	Q61102
RefSeq (mRNA)	NM_004299 NM_001271696 NM_001271697 NM_001271698 NM_001271699	NM_009592
RefSeq (protein)	NP_001258625 NP_001258626 NP_001258627 NP_001258628 NP_004290 NP_001258627.1	NP_033722
Location (UCSC)	Chr X: 75.05 – 75.16 Mb	Chr X: 104.28 – 104.41 Mb
PubMed search

22

11306

ENSG00000131269

ENSMUSG00000031333

O75027

Q61102

NM_004299
NM_001271696
NM_001271697
NM_001271698
NM_001271699

NM_009592

NP_001258627.1

NP_033722

ATP-binding cassette sub-family B member 7, mitochondrial is a protein that in humans is encoded by the ABCB7 gene.

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance as well as antigen presentation. This gene encodes a half-transporter involved in the transport of heme from the mitochondria to the cytosol. With iron/sulfur cluster precursors as its substrates, this protein may play a role in metal homeostasis.

...
Wikipedia