4-fluoroamphetamine

4-Fluoroamphetamine

Clinical data
Pregnancy category	N
Routes of administration	oral
Legal status
Legal status	CA: Schedule I DE: Anlage I (Controlled) UK: Class A
Identifiers
IUPAC name (RS)-1-(4-Fluorophenyl)propan-2-amine
CAS Number	459-02-9 N
PubChem CID	9986
ChemSpider	9592 Y
Chemical and physical data
Formula	C9H12FN
Molar mass	153.20 g/mol
3D model (Jmol)	Interactive image
SMILES Fc1ccc(cc1)CC(N)C
InChI InChI=1S/C9H12FN/c1-7(11)6-8-2-4-9(10)5-3-8/h2-5,7H,6,11H2,1H3 Y Key:DGXWNDGLEOIEGT-UHFFFAOYSA-N Y
NY (what is this?)

4-Fluoroamphetamine (4-FA; 4-FMP; PAL-303; "Flux"), also known as para-fluoroamphetamine (PFA) is a psychoactive research chemical of the phenethylamine and substituted amphetamine chemical classes. It produces stimulant and entactogenic effects, and is described subjectively as being between amphetamine and MDMA. As a recreational drug, 4-FA is sometimes sold along with related compounds such as 2-fluoroamphetamine and 4-fluoromethamphetamine.

4-FA is popular in the Netherlands where it is predominantly used for its specific effects (77% of users) rather than its legal status (18%).

The subjective effects of 4-fluoroamphetamine include euphoria which some find similar to the effects of MDMA and amphetamine, increased energy (stimulation), mood elevation, feelings of warmth and empathy, excessive talking, bruxism, and suppressed appetite (anorexic). The general course of effects involves primarily empathogenic effects for the first few hours, which fades out as increased stimulation develops over the next several hours.

The dopamine reuptake inhibition produced by 4-FA is stronger than that of either 4-CA or 4-IA. 4-FA also produces less hyperthermia than similar compounds such as PMA, 3-MTA and 4-methylamphetamine.

Common acute side effects are nausea, headaches, increased heart rate and insomnia.