4-HO-DET

4-HO-DET

Legal status
Legal status	DE: Anlage I (Controlled) UK: Class A
Identifiers
IUPAC name 3-(2-diethylaminoethyl)-1H-indol-4-ol
CAS Number	22204-89-3 N
PubChem CID	9991554
ChemSpider	8167136 Y
ChEMBL	CHEMBL143202 Y
Chemical and physical data
Formula	C14H20N2O
Molar mass	232.33 g·mol−1
3D model (Jmol)	Interactive image
Melting point	104 to 106 °C (219 to 223 °F)
SMILES Oc1cccc2c1c(cn2)CCN(CC)CC
InChI InChI=1S/C14H20N2O/c1-3-16(4-2)9-8-11-10-15-12-6-5-7-13(17)14(11)12/h5-7,10,15,17H,3-4,8-9H2,1-2H3 Y Key:OHHYMKDBKJPILO-UHFFFAOYSA-N Y
NY (what is this?)

4-HO-DET, also known as 4-hydroxy-diethyl-tryptamine, CZ-74, or ethocin, is a hallucinogenic drug and psychedelic compound of moderate duration. 4-HO-DET is a substituted tryptamine, structurally related to psilocin and 4-HO-DIPT.

The acetic acid ester of 4-HO-DET is known as 4-AcO-DET or ethacetin. The phosphoric acid ester of 4-HO-DET is known as 4-phosphoryloxy-DET, CEY-19, or ethocybin.

4-HO-DET received the lab code CZ-74 in the late 1950s by the inventors of the substance, Albert Hofmann and Franz Troxler. The substance was used together with its phosphoryloxy-analog CEY-19 in human clinical trials in the 1960s by the German researchers Hanscarl Leuner and G. Baer.

10-25mg is the usual oral dosage for 4-HO-DET, while the acetate and phosphate esters are said to require a slightly higher dosage.

Ethocin produces entheogenic effects similar to LSD and psilocybin. Some users have reported unpleasant anxiety and stimulation with this drug, while other accounts label the experience as being much milder than LSD or psilocybin.

Sveriges riksdags health ministry classified 4-HO-DET as "health hazard" under the act (translated Act on the Prohibition of Certain Goods Dangerous to Health) as of Nov 1, 2005, in their regulation SFS 2005:733 listed as 4-hydroxi-N,N-dietyltryptamin (4-HO-DET), making it illegal to sell or possess.