4-Fluorobutyrfentanyl

4-Fluorobutyrfentanyl

Legal status
Legal status	CA: Schedule I UK: Class A US: Unscheduled Illegal in China and Sweden
Identifiers
IUPAC name N-(4-Fluorophenyl)-N-[1-(2-phenylethyl)-4-piperidinyl]-butanamide
CAS Number	244195-31-1
PubChem CID	86280430
ChemSpider	32779976
UNII	2378L0E82T
Chemical and physical data
Formula	C23H29FN2O
Molar mass	368.487563 g/mol
3D model (Jmol)	Interactive image
SMILES CCCC(=O)N(C1CCN(CC1)CCC2=CC=CC=C2)C3=CC=C(C=C3)F
InChI InChI=1S/C23H29FN2O/c1-2-6-23(27)26(21-11-9-20(24)10-12-21)22-14-17-25(18-15-22)16-13-19-7-4-3-5-8-19/h3-5,7-12,22H,2,6,13-18H2,1H3 Key:QZFMCYUBPSLOBP-UHFFFAOYSA-N

4-Fluorobutyrfentanyl (also known as 4-FBF and p-FBF) is an opioid analgesic that is an analog of butyrfentanyl and has been sold online as a designer drug. It is closely related to 4-fluorofentanyl, which has an EC₅₀ value of 4.2 nM for the human μ-opioid receptor.

Side effects of fentanyl analogs are similar to those of fentanyl itself, which include itching, nausea and potentially serious respiratory depression, which can be life-threatening. Fentanyl analogs have killed hundreds of people throughout Europe and the former Soviet republics since the most recent resurgence in use began in Estonia in the early 2000s, and novel derivatives continue to appear.

Sweden's public health agency suggested classifying 4-fluorobutyrfentanyl as hazardous substance on August 18, 2014.

In October 2015, 4-fluorobutyrfentanyl became a controlled substance in China.