21-Hydroxylase

CYP21A2

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
4Y8W,%%s2GEG

Identifiers

Aliases

CYP21A2, CA21H, CAH1, CPS1, CYP21, CYP21B, P450c21B, cytochrome P450 family 21 subfamily A member 2

External IDs

OMIM: 613815 MGI: 88591 HomoloGene: 68063 GeneCards: CYP21A2

EC number

1.14.99.10

Gene ontology
Molecular function	• iron ion binding • metal ion binding • monooxygenase activity • steroid hydroxylase activity • steroid binding • heme binding • oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen • oxidoreductase activity • lipid binding • steroid 21-monooxygenase activity
Cellular component	• organelle membrane • endoplasmic reticulum membrane • membrane • intracellular membrane-bounded organelle • endoplasmic reticulum
Biological process	• glucocorticoid biosynthetic process • mineralocorticoid biosynthetic process • sterol metabolic process • oxidation-reduction process • steroid biosynthetic process • steroid metabolic process
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


1589


13079

Ensembl


n/a


ENSMUSG00000024365

UniProt


P08686 Q08AG9


P03940

RefSeq (mRNA)


NM_000500 NM_001128590


NM_009995

RefSeq (protein)


NP_000491 NP_001122062 NP_000491.4 NP_001122062.3


NP_034125.2 NP_034125

Location (UCSC)

Chr 6: 32.04 – 32.04 Mb

Chr 17: 34.8 – 34.8 Mb

PubMed search

Steroid 21-monooxygenase

Identifiers

Databases

PDB structures

AmiGO / EGO

Search
PMC	articles
PubMed	articles
NCBI	proteins

Search
PMC	articles
PubMed	articles
NCBI	proteins

4Y8W,%%s2GEG

n/a

NM_000500
NM_001128590

NM_009995

NP_000491
NP_001122062
NP_000491.4
NP_001122062.3

NP_034125.2
NP_034125

Steroid 21-hydroxylase is a enzyme that is involved with the biosynthesis of the steroid hormones aldosterone and cortisol.

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