2016 Conference USA football standings
	Conf				Overall
Team		W		L		W		L
East Division
WKU xy$		7	–	1		11	–	3
Old Dominion x		7	–	1		10	–	3
Middle Tennessee		5	–	3		8	–	5
FIU		4	–	4		4	–	8
Charlotte		3	–	5		4	–	8
Marshall		2	–	6		3	–	9
Florida Atlantic		2	–	6		3	–	9
West Division
Louisiana Tech xy		6	–	2		9	–	5
UTSA		5	–	3		6	–	7
Southern Miss		4	–	4		7	–	6
North Texas		3	–	5		5	–	8
Rice		2	–	6		3	–	9
UTEP		2	–	6		4	–	8

Championship: Western Kentucky 58, Louisiana Tech 44
$ – Conference champion x – Division champion/co-champions As of January 30, 2017; Rankings from AP Poll

The 2016 Middle Tennessee Blue Raiders football team represented Middle Tennessee State University in the 2016 NCAA Division I FBS football season. The Blue Raiders played their home games at the Johnny "Red" Floyd Stadium in Murfreesboro, Tennessee, and competed in the East Division of Conference USA (C–USA). They were led by 11th-year head coach . They finished the season 8–5, 5–3 in C-USA play to finish in third place in the East Division. They were invited to the Hawaii Bowl where they lost to Hawaii.

Middle Tennessee announced its 2016 football schedule on February 4, 2016. The 2016 schedule consists of 5 home and 7 away games in the regular season. The Blue Raiders will host C–USA foes Florida Atlantic, Louisiana Tech, UTSA, and Western Kentucky (WKU), and will travel to Charlotte, Florida International (FIU), Marshall, and North Texas.

The team will play four non–conference games, a home games against Alabama A&M from the Southwestern Athletic Conference, and three road games against Bowling Green from the Mid-American Conference (MAC), Missouri and Vanderbilt both from the Southeastern Conference (SEC).