2013 Winston-Salem Open – Singles
| Singles | |
|---|---|
| 2013 Winston-Salem Open | |
| Champion |
 Jürgen Melzer
|
| Runner-up |
 Gaël Monfils
|
| Final score | 6–3, 2–1, ret. |
John Isner was the two-time defending champion, but withdrew from the tournament because of a hip injury.
Jürgen Melzer won the title, defeating Gaël Monfils in the final, 6–3, 2–1, ret.
All seeds received a bye into the second round.
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