The 2012 NCAA Division I Men's Basketball Championship Game was the finals of the 2012 NCAA Division I Men's Basketball Tournament and it determined the national champion for the 2011-12 NCAA Division I men's basketball season. The 2012 National Title Game was played on April 2, 2012 at the Mercedes-Benz Superdome in New Orleans, Louisiana, and featured the 2012 South Regional Champions, #1-seeded Kentucky and the 2012 Midwest Regional Champions, #2-seeded Kansas. The two head coaches for this game, Kentucky's John Calipari and Kansas's Bill Self also coached at the 2008 National Championship Game where Bill Self was coaching for Kansas and John Calipari was coaching for Memphis. The two teams met in the regular season at the 2011 Champions Classic and Kentucky won that game 75-65.

Kansas entered the 2012 tournament as the #2 seed in the Midwest Regional. In the 2nd Round, Thomas Robinson had a double-double with 16 points and 13 rebounds as Kansas beat Detroit 65-50. In the 3rd round against Purdue trailing 60-59, Elijah Johnson got the steal and layup to take a 61-60 lead and with 3 seconds left, Tyshawn Taylor made a dunk for a 63-60 win. In the Sweet 16 against NC State, Jeff Withey blocked 10 shots to survive with a 60-57 victory. In the Elite Eight, Tyshawn Taylor finally got hot with 22 points, 6 rebounds, 5 assists, and 5 steals as Kansas beat North Carolina 80-67 to advance to the Final Four. In the 2012 Final Four, Ohio State got off to a strong start and had a 26-13 lead at one point and then, Kansas managed to control Jared Sullinger to beat the Buckeyes 64-62 and advance to the 2012 National Championship Game.

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