The USA Sevens is played annually as part of the IRB Sevens World Series for international rugby sevens (seven-a-side version of rugby union). The 2010 competition, which took place on February 13 and February 14 at Sam Boyd Stadium Whitney, Nevada, was the fourth Cup trophy in the 2009–10 IRB Sevens World Series. It was the first edition of the USA Sevens to be held in the Las Vegas area; the tournament had been hosted by the Los Angeles suburb of Carson, California from 2004 to 2006 and by San Diego from 2007 to 2009.
Samoa won the Cup final 33–12 over New Zealand. The Plate went to defending series champion South Africa, the Bowl was won by the homestanding USA, and the Shield went to Scotland.