2010 Tallahassee Tennis Challenger – Singles
| Singles | |
|---|---|
| 2010 Tallahassee Tennis Challenger | |
| Champion |
 Brian Dabul
|
| Runner-up |
 Robby Ginepri
|
| Final score | 4–6, 4–0, Ret. |
John Isner was the defending of champion, but he chose not to participate this year.
Brian Dabul won in the final, after Robby Ginepri retired at the score of 6–4, 0–4.
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