The 2010–11 Taça de Portugal, also known as Taça de Portugal Millennium for sponsorship reasons, was the 71st season of the Taça de Portugal. A total of 172 clubs from all four tiers of Portuguese football took part in this tournament. In the final (played at the Estádio Nacional, in Oeiras), Porto beat Vitória de Guimarães by 6–2, in a reedition of the 1988 final.

The following teams took part in this competition:

In this round entered teams from Second Division (3rd level) and Third Division (4th level). Twenty teams received a bye to the Second Round: 1º de Maio (III), Alcochetense (III), Aliados Lordelo (II), Amarante (III), Atlético da Malveira (III), Camacha (II), Coimbrões (II), Esposende (III), Limianos (III), Maria da Fonte (III), Mondinense (III), Monsanto (III), Moura (III), Paredes (III), Penalva do Castelo (III), Pontassolense (II), Praiense (II), Sousense (III), Tirsense (II) and Tondela (II). The matches were played on September 4 and 5, 2010.

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