The 2009 National League Division Series (NLDS) consisted of two concurrent best-of-five game series that determined the participating teams in the 2009 National League Championship Series. Three divisional winners and a "wild card" team played in the two series. The NLDS began on Wednesday, October 7 and ended on Monday, October 12. TBS televised all games in the United States. The matchups were:

This marked the second postseason meeting between the Phillies and Rockies in three seasons; the Rockies swept the Phillies in the 2007 NLDS. The Dodgers and Cardinals last met in the postseason during the 2004 NLDS, which the Cardinals won 3–1.

The Dodgers and Phillies won their respective series—the Dodgers three games to none and the Phillies three games to one. The Phillies defeated the Dodgers in the NLCS by a series score of 4–1, and lost the 2009 World Series to the New York Yankees, 4–2.

Los Angeles won the series, 3–0.

Philadelphia won the series, 3–1.

9:37 p.m. (ET) at Dodger Stadium in Los Angeles, California

Neither team's starting pitcher was particularly effective in the series opener; however, neither team's offense was able to capitalize, as this game set a MLB postseason record for runners left on base combined between the two teams, with 30. Los Angeles starter Randy Wolf loaded the bases with no outs in the first inning, allowing one run to score on a fielding miscue. In the bottom half of the inning, St. Louis starter Chris Carpenter gave up a two-run home run to Matt Kemp, giving the Dodgers a lead they would never relinquish. The St. Louis bullpen gave up only one run over three innings, while the Los Angeles bullpen gave up one run over 5 ¹⁄₃ innings. Los Angeles slugger Manny Ramirez was held to 1-for-4 with one walk, while St. Louis slugger Albert Pujols was 0-for-3 with two intentional walks.

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