2008 Conference USA football standings
	Conf				Overall
Team		W		L		W		L
East Division
East Carolina x$		6	–	2		9	–	5
Memphis		4	–	4		6	–	7
Southern Miss		4	–	4		7	–	6
UAB		3	–	5		4	–	8
UCF		3	–	5		4	–	8
Marshall		3	–	5		4	–	8
West Division
Tulsa xy		7	–	1		11	–	3
Rice x		7	–	1		10	–	3
Houston		6	–	2		8	–	5
UTEP		4	–	4		5	–	7
Tulane		1	–	7		2	–	10
SMU		0	–	8		1	–	11
Championship: East Carolina 27, Tulsa 24
$ – Conference champion x – Division champion/co-champions y – Championship game participant Rankings from AP Poll

The 2008 Memphis Tigers football team represented the University of Memphis in the 2008 NCAA Division I FBS football season. Memphis competed as a member of the Conference USA. The team was led by head coach Tommy West. The Tigers played their home games at the Liberty Bowl Memorial Stadium. The Tigers finished the regular season with a 6–6 record, which was enough to attain bowl eligibility. Memphis accepted a bid to play against South Florida in the inaugural St. Petersburg Bowl in St. Petersburg, Florida. The Tigers lost, 41–14.