The 2006–07 Detroit Pistons season was the 66th season of the franchise, the 59th in the National Basketball Association (NBA), and the 50th in the Detroit area. The Pistons began the season hoping to improve upon their 64–18 output from the previous season. However, they came eleven wins shy of tying it, finishing 53–29. After signing Nazr Mohammed and hometown native Chris Webber to offset the loss of Ben Wallace during the off-season, the Pistons were able to reach the Eastern Conference finals for the fifth consecutive season, becoming the first team since the 1992–93 Chicago Bulls to do so. They were defeated by the eventual Eastern Conference champion Cleveland Cavaliers.

^*Qualified for playoffs

(1) Detroit Pistons vs. (8) Orlando Magic

Last Playoff Meeting: 2003 Eastern Conference First Round (Detroit won 4-3)

(1) Detroit Pistons vs. (5) Chicago Bulls

Last Playoff Meeting: 1991 Eastern Conference Finals (Chicago won 4-0)

(1) Detroit Pistons vs. (2) Cleveland Cavaliers

Last Playoff Meeting: 2006 Eastern Conference Semifinals (Detroit won 4-3)

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