The 2nd Fußball-Bundesliga (women) 2005–06 was the 2nd season of the 2. Fußball-Bundesliga (women), Germany's second football league. It began on 14 August 2005 and ended on 5 June 2006.
Pld = Matches played; W = Matches won; D = Matches drawn; L = Matches lost; GF = Goals for; GA = Goals against; GD = Goal difference; Pts = Points
* VfL Singelfingen was relegated to the 2. Bundesliga therefore Sindelfingen II was automatically relegated to the Regionalliga instead of Karlsruher SC.
Pld = Matches played; W = Matches won; D = Matches drawn; L = Matches lost; GF = Goals for; GA = Goals against; GD = Goal difference; Pts = Points