The 1983 World Series matched the American League champion Baltimore Orioles against the National League champion Philadelphia Phillies, with the Orioles winning four games to one. "The I-95 Series", like the World Series two years later, also took its nickname from the interstate that the teams and fans traveled on, Interstate 95 in this case. This was the last World Series that Bowie Kuhn presided over as commissioner.

This is Baltimore's most recent World Series title, and also their most recent American League pennant.

This was the first World Series since 1956 in which the teams did not use air travel. Baltimore and Philadelphia are approximately 100 miles apart on Interstate 95.

The Orioles were led by first-year manager Joe Altobelli, who succeeded Earl Weaver; Weaver retired to the broadcast booth after a sixteen-year managerial run from 1968 to 1982. Altobelli inherited a lineup led by first baseman Eddie Murray and shortstop Cal Ripken, Jr. Ripken (.318 BA, 27 HR, 102 RBI) and Murray (.306, 33, 111) finished first and second in the 1983 MVP voting, with Ripken out-pointing Murray, 322–290. Veteran outfielder Ken Singleton settled into the DH role, while the rest of the team was a corps of platoon players. The Orioles finished first in the AL in team home runs (168); first in OBP (.340); and second in runs, doubles, and walks.

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