1981 U.S. Open - Men's Singles
| Men's Singles | |
|---|---|
| 1981 US Open | |
| Champion |
 John McEnroe
|
| Runner-up |
 Björn Borg
|
| Final score | 4–6, 6–2, 6–4, 6–3 |
John McEnroe was the two time defending champion and retained his title again, defeating Björn Borg 4–6, 6–2, 6–4, 6–3 in the final to win the Men's Singles tennis title at the 1981 US Open in a repeat of the previous years final, and which turned out to be Borg's final grand slam match.
The seeded players are listed below. John McEnroe is the champion; others show the round in which they were eliminated.
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