The 1980 U.S. Pro Indoor was a men's tennis tournament played on indoor carpet courts that was part of World Championship Tennis (WCT) category of tournaments of the 1980 Volvo Grand Prix circuit. It was played at the Wachovia Spectrum in Philadelphia, Pennsylvania in the United States and was held from January 21 through January 27, 1980. First-seeded Jimmy Connors won the singles title after a final that lasted three hours and 30 minutes and earned $40,000 first-prize money. It was his fourth singles title at the tournament which equalled the record held by Rod Laver.

Jimmy Connors defeated John McEnroe 6–3, 2–6, 6–3, 3–6, 6–4

Peter Fleming / John McEnroe defeated Brian Gottfried / Raúl Ramírez 6–3, 7–6