1966 U.S. National Championships – Women's Singles
| Women's Singles | |
|---|---|
| 1966 U.S. National Championships | |
| Champion |
 Maria Bueno
|
| Runner-up |
 Nancy Richey
|
| Final score | 6–3, 6–1 |
Second-seeded Maria Bueno defeated Nancy Richey 6–3, 6–1 in the final to win the Women's Singles tennis title at the 1966 U.S. National Championships.
The seeded players are listed below. Maria Bueno is the champion; others show in brackets the round in which they were eliminated.
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