The 1959 Grand Prix motorcycle racing season was the 11th Road Racing World Championship Grand Prix season. The season consisted of seven Grand Prix races in five classes: 500cc, 350cc, 250cc, 125cc and Sidecars 500cc. It began on 17 May, with French Grand Prix and ended with Nations Grand Prix in Italy on 6 September.
† Race did not count towards the World Championship.
†† The Nations Grand Prix also held a non-championship 175 cc race, won by the Italian, Francesco Villa.
Points were awarded to the top six finishers in each race. Only the four best races were counted in all five classes: the Sidecars, 125cc, 250cc, 350cc and 500cc championships.
Bold – Pole
Italics – Fastest Lap