11β-hydroxysteroid dehydrogenase type 1

HSD11B1
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 4P38, 1XU7, 1XU9, 2BEL, 2ILT, 2IRW, 2RBE, 3BYZ, 3BZU, 3CH6, 3CZR, 3D3E, 3D4N, 3D5Q, 3EY4, 3FCO, 3FRJ, 3H6K, 3HFG, 3OQ1, 3PDJ, 3QQP, 3TFQ, 4BB5, 4BB6, 4C7J, 4C7K, 4HFR, 4HX5, 4IJU, 4IJV, 4IJW, 4K1L, 4YYZ
Identifiers
Aliases	HSD11B1, 11-DH, 11-beta-HSD1, CORTRD2, HDL, HSD11, HSD11B, HSD11L, SDR26C1, hydroxysteroid (11-beta) dehydrogenase 1, hydroxysteroid 11-beta dehydrogenase 1
External IDs	OMIM: 600713 MGI: 103562 HomoloGene: 68471 GeneCards: HSD11B1
EC number	1.1.1.146
Gene ontology Molecular function • 11-beta-hydroxysteroid dehydrogenase (NADP+) activity • oxidoreductase activity • 11-beta-hydroxysteroid dehydrogenase [NAD(P) activity] Cellular component • integral component of membrane • endoplasmic reticulum membrane • endoplasmic reticulum • membrane Biological process • glucocorticoid biosynthetic process • oxidation-reduction process • lung development • lipid metabolic process • steroid metabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	3290	15483
Ensembl	ENSG00000117594	ENSMUSG00000016194
UniProt	P28845	P50172
RefSeq (mRNA)	NM_181755 NM_001206741 NM_005525	NM_001044751 NM_008288
RefSeq (protein)	NP_001193670 NP_005516 NP_861420 NP_001193670.1 NP_005516.1 NP_861420.1	NP_001038216.1 NP_032314.2 NP_001038216 NP_032314
Location (UCSC)	Chr 1: 209.69 – 209.73 Mb	Chr 1: 193.22 – 193.26 Mb
PubMed search

4P38, 1XU7, 1XU9, 2BEL, 2ILT, 2IRW, 2RBE, 3BYZ, 3BZU, 3CH6, 3CZR, 3D3E, 3D4N, 3D5Q, 3EY4, 3FCO, 3FRJ, 3H6K, 3HFG, 3OQ1, 3PDJ, 3QQP, 3TFQ, 4BB5, 4BB6, 4C7J, 4C7K, 4HFR, 4HX5, 4IJU, 4IJV, 4IJW, 4K1L, 4YYZ

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