Α2-HS-glycoprotein

AHSG
Identifiers
Aliases	AHSG, A2HS, AHS, FETUA, HSGA, alpha-2-HS-glycoprotein, alpha 2-HS glycoprotein
External IDs	MGI: 107189 HomoloGene: 1225 GeneCards: AHSG
Gene location (Human) Chr. Chromosome 3 (human) Band n/a Start 186,612,923 bp End 186,621,318 bp
Gene location (Mouse) Chr. Chromosome 16 (mouse) Band 16 B1|16 13.74 cM Start 22,892,042 bp End 22,899,438 bp
RNA expression pattern More reference expression data
Gene ontology Molecular function • endopeptidase inhibitor activity • cysteine-type endopeptidase inhibitor activity • kinase inhibitor activity Cellular component • blood microparticle • extracellular exosome • platelet alpha granule lumen • extracellular space • Golgi apparatus • secretory granule lumen • endoplasmic reticulum lumen • extracellular matrix • extracellular region Biological process • regulation of bone mineralization • negative regulation of biomineral tissue development • skeletal system development • negative regulation of insulin receptor signaling pathway • positive regulation of phagocytosis • pinocytosis • negative regulation of bone mineralization • acute-phase response • ossification • regulation of inflammatory response • negative regulation of phosphorylation • platelet degranulation • negative regulation of endopeptidase activity • neutrophil degranulation • post-translational protein modification • cellular protein metabolic process Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	197	11625
Ensembl	ENSG00000145192	ENSMUSG00000022868
UniProt	P02765	P29699
RefSeq (mRNA)	NM_001622	NM_001276449 NM_001276450 NM_013465
RefSeq (protein)	NP_001613 NP_001341500 NP_001341501 NP_001341502	NP_001263378 NP_001263379 NP_038493
Location (UCSC)	Chr 3: 186.61 – 186.62 Mb	Chr 3: 22.89 – 22.9 Mb
PubMed search

197

11625

ENSG00000145192

ENSMUSG00000022868

P02765

P29699

NM_001622

NM_001276449
NM_001276450
NM_013465

NP_001613
NP_001341500
NP_001341501
NP_001341502

NP_001263378
NP_001263379
NP_038493

alpha-2-HS-glycoprotein (AHSG) also known as fetuin-A is a protein that in humans is encoded by the AHSG gene. Fetuin-A belongs to the fetuin class of plasma binding proteins and is more abundant in fetal than adult blood.

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Wikipedia