Α-galactosidase A

GLA
Available structures PDB Ortholog search: PDBe RCSB List of PDB id codes 1R46, 1R47, 3GXN, 3GXP, 3GXT, 3HG2, 3HG3, 3HG4, 3HG5, 3LX9, 3LXA, 3LXB, 3LXC, 3S5Y, 3S5Z, 3TV8, 4NXS
Identifiers
Aliases	GLA, GALA, galactosidase alpha
External IDs	MGI: 1347344 HomoloGene: 90852 GeneCards: GLA
Gene ontology Molecular function • hydrolase activity, hydrolyzing O-glycosyl compounds • protein homodimerization activity • hydrolase activity, acting on glycosyl bonds • raffinose alpha-galactosidase activity • protein binding • galactoside binding • catalytic activity • receptor binding • hydrolase activity • alpha-galactosidase activity Cellular component • cytoplasm • Golgi apparatus • lysosomal lumen • lysosome • extracellular exosome • extracellular region • azurophil granule lumen Biological process • negative regulation of nitric-oxide synthase activity • glycosphingolipid metabolic process • glycosphingolipid catabolic process • carbohydrate metabolic process • negative regulation of nitric oxide biosynthetic process • metabolic process • oligosaccharide metabolic process • neutrophil degranulation • glycoside catabolic process • glycosylceramide catabolic process Sources:Amigo / QuickGO
RNA expression pattern
More reference expression data
Orthologs
Species	Human	Mouse
Entrez	2717	11605
Ensembl	ENSG00000102393	ENSMUSG00000031266
UniProt	P06280	P51569
RefSeq (mRNA)	NM_000169	NM_013463
RefSeq (protein)	NP_000160	n/a
Location (UCSC)	Chr X: 101.4 – 101.41 Mb	Chr X: 134.59 – 134.6 Mb
PubMed search

alpha-galactosidase
Identifiers
EC number	3.2.1.22
CAS number	9025-35-8
Databases
IntEnz	IntEnz view
BRENDA	BRENDA entry
ExPASy	NiceZyme view
KEGG	KEGG entry
MetaCyc	metabolic pathway
PRIAM	profile
PDB structures	RCSB PDB PDBe PDBsum
Gene Ontology	AmiGO / EGO
Search PMC articles PubMed articles NCBI proteins

Search
PMC	articles
PubMed	articles
NCBI	proteins

1R46, 1R47, 3GXN, 3GXP, 3GXT, 3HG2, 3HG3, 3HG4, 3HG5, 3LX9, 3LXA, 3LXB, 3LXC, 3S5Y, 3S5Z, 3TV8, 4NXS

2717

11605

ENSG00000102393

ENSMUSG00000031266

P06280

P51569

NM_000169

...
Wikipedia