A prime meridian is a meridian (a line of longitude) in a geographical coordinate system at which longitude is defined to be 0°. Together, a prime meridian and its antimeridian (the 180th meridian in a 360°-system) form a great circle. This great circle divides the sphere, e.g., the Earth, into two hemispheres. If one uses directions of East and West from a defined prime meridian, then they can be called Eastern Hemisphere and Western Hemisphere.
A prime meridian is ultimately arbitrary, unlike an equator, which is determined by the axis of rotation—and various conventions have been used or advocated in different regions and throughout history. The most widely used modern meridian is the IERS Reference Meridian. It is derived but deviates slightly from the Greenwich Meridian, which was selected as an international standard in 1884.
The notion of longitude was developed by the Greek Eratosthenes (c. 276 BC – c. 195 BC) in Alexandria, and Hipparchus (c. 190 BC – c. 120 BC) in Rhodes, and applied to a large number of cities by the geographer Strabo (64/63 BC – c. 24 AD). But it was Ptolemy (c. AD 90 – c. AD 168) who first used a consistent meridian for a world map in his Geographia.
Ptolemy used as his basis the "Fortunate Isles", a group of islands in the Atlantic which are usually associated with the Canary Islands (13° to 18°W), although his maps correspond more closely to the Cape Verde islands (22° to 25° W). The main point is to be comfortably west of the western tip of Africa (17.5° W) as negative numbers were not yet in use. His prime meridian corresponds to 18° 40' west of Winchester (about 20°W) today. At that time the chief method of determining longitude was by using the reported times of lunar eclipses in different countries.