Yñigo Ortiz de Retez (fl. 1545) was a 16th-century Spanish maritime explorer of Basque origin, who navigated the northern coastline of the Pacific–Melanesian island of New Guinea, and is credited with bestowing the island's name ("Nueva Guinea").
Yñigo Ortiz de Retez was born in Retes de Llanteno (Alava, Spain) in a non-titled nobility family (hidalgos) in the first decade of the 16th century. The first accounts we have of him are as part of Alvarado's expedition of 1538 to take the governorship of Guatemala and Honduras. He participated in the expedition to relieve the siege of Nochistlán in 1541 during the Mixtón war, led by Alvarado. In 1542 he was appointed to the expedition of Lopez de Villalobos to the Islas de Poniente (Philippines). Upon his arrival in Mindanao on February 1543, Ortiz de Retes was promoted to Maestre de Campo.
After the unsuccessful attempt of Bernardo de la Torre in 1543 to make the round trip and return to Mexico, López de Villalobos commissioned Ortiz de Retez for the same mission but this time taking a more southerly route. On 16 May 1545 Ortiz de Retez, in command of the San Juan de Letran, left port in Tidore, an island which was Spain's stronghold in the Maluku Islands and going by way of the Talaud Islands and the Schoutens, reached the northern coast of New Guinea, which was coasted till the end of August when, having got to the 5°S latitude, contrary winds and currents forced a return to Tidore where he arrived on 5 October 1545. Many islands were encountered and first charted, along the northern coast of New Guinea, and in the Padaidos, Le Maires, Ninigos, Kaniets and Hermits, to some of which Spanish names were given.