XK (protein)
| XK (protein) | |
|---|---|
| Identifiers | |
| Symbol | XK |
| Alt. symbols | XKR1, Kx, X1k |
| Entrez | 7504 |
| HUGO | 12811 |
| OMIM | 314850 |
| PDB | BAE48708 |
| RefSeq | NM_021083 |
| UniProt | P51811 |
| Other data | |
| Locus | Chr. X p21.2-p21.1 |
XK (also known as Kell blood group precursor) is a protein found on human red blood cells and other tissues which is responsible for the Kx antigen which helps determine a person's blood type.
The Kx antigen plays a role in matching blood for blood transfusions.
Mutation of XK protein may lead to McLeod syndrome, a multi-system disorder characterized by hemolytic anemia, myopathy, acanthocytosis, and chorea.
XK is located on the X chromosome (cytogenetic band Xp21.1) and absence of the XK protein is an X-linked disease.
XK is a membrane transport protein of unknown action.
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