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Work-up (chemistry)


In chemistry, work-up refers to the series of manipulations required to isolate and purify the product(s) of a chemical reaction.

Typically, these manipulations may include:

For example, the Grignard reaction between phenylmagnesium bromide and carbon dioxide in the form of dry ice gives the conjugate base of benzoic acid. The desired product, benzoic acid, is obtained by the following work-up:

Benzoic acid synthesis.png


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