William Cavendish, 2nd Baron Chesham

William George Cavendish, 2nd Baron Chesham (29 October 1815 – 26 June 1882) was a British Liberal politician.

A member of the Cavendish family headed by the Duke of Devonshire, Chesham was the son of Charles Compton Cavendish, 1st Baron Chesham and Lady Catherine Susan Gordon, daughter of George Gordon, 9th Marquess of Huntly. In 1847 he was elected Member of Parliament for Peterborough, a seat he held until 1852, and later represented Buckinghamshire from 1857 to 1863, when he succeeded his father in the Barony and took his seat in the House of Lords.

In 1849 Lord Chesham married Henrietta Frances Lascelles, daughter of William Saunders Sebright Lascelles and his wife Lady Caroline Georgiana Howard, daughter of George Howard, 6th Earl of Carlisle. He died in June 1882, aged 66, and was succeeded in the barony by his eldest son Charles Compton William Cavendish. His daughter Katherine Cavendish (1857–1941) married Hugh Grosvenor, 1st Duke of Westminster, as his second wife.