David Wilfred Abse (15 March 1915 – 4 November 2005) was a Welsh psychiatrist.
Abse was born in Cardiff, a brother of the poet Dannie Abse (1923–2014) and the politician Leo Abse (1917–2008). A psychoanalyst, Abse spent the greater part of his career in Charlottesville, Virginia where he was a professor of psychiatry at the University of Virginia from 1962 until 2000. Abse was known for his work in group therapy and hysteria, and contributed to the Journal of Nervous and Mental Disease. It was said that his younger brother Leo got his habit of Freudian allusion in his speeches from Wilfred.