"What Happens Tomorrow" is a song by British pop rock band Duran Duran and is featured on their 2004 album, Astronaut. It was also released in January 2005 as the second single from that album, and the band's thirty-third single overall. The single debuted at #11 in the UK Singles Chart on 6 February 2005 (see 2005 in British music).

The track was originally debuted on an American internet radio station in 2003 while the band were hunting around for a record deal. During the outro, bassist John Taylor announced that it would be a single later on in the year.

The version of "What Happens Tomorrow" played on the radio was an early demo featuring an extended bridge, which would be removed by the time the track was released on Astronaut; parts of the track were re-worked to become the b-side "Silent Icy River".

The video, which showed the band as constellations, was directed by the duo of Smith n' Borin (Frank Buff Borin and Ryan Smith). It was nominated on the Visual Effects Society Awards 2005 for "Outstanding Visual Effects in a Music Video" for media artists Jerry Steele, Jo Steele, Brian Adler and Monique Eissing.

Playboy Playmate Nicole Marie Lenz appears in the video.

B-sides on various releases included "(Reach Up For The) Sunrise (Eric Prydz Mix)", "Silent Icy River", and "What Happens Tomorrow (Harry Peat Mix)".

In 2005, "What Happens Tomorrow" was used in a promotional spot for the U.S. digital cable network Fox Soccer Channel; Simon Le Bon and John Taylor had also appeared in a separate spot for the network.

It was also used in a promotional spot for Flight 29 Down on Canada's Family Channel.

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