The Walter Reed Biosystematics Unit ("WRBU") is a US Army organization that conducts laboratory and field research on the systematics of medically important arthropods in support of epidemiological investigations and disease prevention and control strategies of importance to the military. Research is carried out worldwide, within geographic or faunistic restrictions of the material available and military requirements. Research efforts focus on the development of accurate and reliable means of identifying vectors of arbopathogens of humans.
The WRBU also performs arthropod collections management for the Department of Entomology, National Museum of Natural History mosquito collection and maintains a molecular entomology laboratory within the Smithsonian Institution Museum Support Center for joint use of WRBU and National Museum of Natural History (NMNH) personnel.
Army entomologists began formal collaborations with Smithsonian Institution entomologists as early as 1961. The WRBU's unit lineage begins with the stand up of the Army Mosquito Project (AMP) in 1964. In 1966, the AMP's mission was refocused on the vectorborne disease threat facing troops deployed to southeast Asia for the Vietnam conflict and the unit was reorganized as the Southeast Asia Mosquito Project (SEAMP). After the war in southeast Asia wound down, SEAMP was reorganized in 1974 as the Medical Entomology Project (MEP) to encompass a broader long-term mission. In 1981, the MEP was reorganized as the Walter Reed Biosystematics Unit, and the unit has retained that identity through subsequent moves and restructurings. The name commemorates U.S. Army physician Major Walter Reed who in 1901 led the team that established that yellow fever is transmitted by mosquitoes.