Vladimir Mikhailovich Myasishchev (Russian: Владимир Михайлович Мясищев) (September 28, 1902 in Yefremov – October 14, 1978 in Moscow) was a Soviet aircraft designer, Major General of Engineering (1944), Hero of Socialist Labor (1957), Doctor of Technical Sciences (1959), Honored Science Worker of the RSFSR (1972).
After his graduation from Moscow State Technical University in 1926, Myasishchev worked at the Tupolev Design Bureau and took part in constructing airplanes, such as TB-1, TB-3, and Tupolev ANT-20 Maxim Gorky. As an assistant to Boris Pavlovich Lisunov, he traveled to the United States in 1937 to help translate the Douglas DC-3 drawings in preparation for the production of the Lisunov Li-2.
In 1938, Myasishchev became a victim of a repression campaign. While in confinement, he worked at NKVD's Central Design Bureau No. 29 (ЦКБ-29 НКВД) in Moscow under the guidance of Vladimir Petlyakov, designing the Pe-2 bomber. In 1940, after his release, Myasishchev headed a design bureau (in the same building), working on the long-range high-altitude bomber DVB-102 (ДВБ-102). In 1946–1951, Myasishchev was the head of the faculty and later dean of the Department of Aircraft Design at Moscow Aviation Institute. In 1956, he became chief aircraft designer. In 1960–1967, Myasishchev was appointed Head of the Central Aerohydrodynamic Institute (TsAGI). In 1967–1978, Myasishchev held a post of the chief aircraft designer of the Experimental Machine Building Factory, which would bear his name starting 1981.