Michael Vincent O'Brien (9 April 1917 – 1 June 2009) was an Irish race horse trainer from Churchtown, County Cork, Ireland. In 2003 he was voted the greatest influence in horse racing history in a worldwide poll hosted by the Racing Post. In earlier Racing Post polls he was voted the best ever trainer of national hunt and of flat racehorses. He trained six horses to win the Epsom Derby, was twice British champion trainer, won three Grand Nationals in succession and trained the only British Triple Crown winner since the Second World War. Aidan O'Brien (no relation) took over the Ballydoyle stables after his retirement.
In his early days Vincent O'Brien was a trainer of steeplechasers and hurdlers, and won the Grand National at Liverpool three times in succession, with three different horses – Early Mist in 1953, Royal Tan in 1954, and Quare Times in 1955. The greatest steeplechaser he trained was Cottage Rake, which won the Cheltenham Gold Cup three times in succession (1948–1950). He later trained Knock Hard to also win the Cheltenham Gold Cup (1953). He also won the Champion Hurdle three years in succession with Hatton's Grace (1949–1951).
Soon after his third Grand National triumph, he turned his attention to flat racing, and set up his stables at Ballydoyle, near Cashel, County Tipperary. Ballymoss, owned by American businessman John McShain, was O'Brien's first top-flight flat racing horse. This colt won the Irish Derby Stakes and England's St. Leger Stakes in 1957 and France's Prix de l'Arc de Triomphe in 1958, en route to earning European Horse of the Year honours. For another American, Alice du Pont Mills, he trained the filly Glad Rags who in 1966 gave him his only win in the 1,000 Guineas Stakes. O'Brien's first Epsom Derby winner was Larkspur in 1962. His other Derby winners were Sir Ivor (1968), Nijinsky (1970), Roberto (1972), The Minstrel (1977) and finally Golden Fleece (1982). O'Brien also trained the brilliant dual Prix de L'Arc de Triomphe winner, Alleged, which triumphed in 1977 and 1978.