Venetian Ceruse, also known as Spirits of Saturn, was a 16th-century cosmetic used as a skin whitener. It was in great demand and considered the best available at that time.
The cosmetic's use of white lead as a pigment caused lead poisoning, damaging the skin and causing hair loss. Usage over an extended period could cause death.
Elizabeth I of England is popularly imagined to have been a notable user, although critics Anna Riehl and Kate Maltby have argued that little historical evidence exists to support this claim.