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Uterine leiomyoma

Uterine fibroids
Synonyms Uterine leiomyoma, uterine myoma, myoma, fibromyoma, fibroleiomyoma
Uterine fibroids.jpg
Uterine fibroids as seen during laparoscopic surgery
Specialty Gynecology
Symptoms Painful or heavy periods
Complications Infertility
Usual onset Middle and later reproductive years
Causes Unknown
Risk factors Family history, obesity, eating red meat
Diagnostic method Pelvic examination, medical imaging
Similar conditions Leiomyosarcoma, pregnancy, ovarian cyst, ovarian cancer
Treatment Medications, surgery, uterine artery embolization
Medication Ibuprofen, paracetamol (acetaminophen), iron supplements, gonadotropin releasing hormone agonist
Prognosis Improve after menopause
Frequency ~50% of women by age 50
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Uterine fibroids, also known as uterine leiomyomas or fibroids, are benign smooth muscle tumors of the uterus. Most women have no symptoms while others may have painful or heavy periods. If large enough, they may push on the bladder causing a frequent need to urinate. They may also cause pain during sex or lower back pain. A woman can have one uterine fibroid or many. Occasionally, fibroids may make it difficult to become pregnant, although this is uncommon.

The exact cause of uterine fibroids is unclear. However, fibroids run in families and appear to be partly determined by hormone levels. Risk factors include obesity and eating red meat. Diagnosis can be performed by pelvic examination or medical imaging.

Treatment is typically not needed if there are no symptoms.NSAIDs, such as ibuprofen, may help with pain and bleeding while paracetamol (acetaminophen) may help with pain.Iron supplements may be needed in those with heavy periods. Medications of the gonadotropin releasing hormone agonist class may decrease the size of the fibroids but are expensive and associated with side effects. If greater symptoms are present, surgery to remove the fibroid or uterus may help.Uterine artery embolization may also help.Cancerous versions of fibroids are very rare and are known as leiomyosarcomas. They do not appear to develop from benign fibroids.


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