Urinothorax (pl. urinothoraces) means urine in the fluid-filled cavity that surrounds the lungs. It is a rare cause of pleural effusion secondary to obstructive uropathy whereby urine forms a collection in the pleural cavity. The urine arrives in the pleural space either retroperitoneally under the posterior diaphragm, or via the retroperitoneal lymphatics. It remains a rare, possibly under-diagnosed, differential in the case of transudative pleural effusion.
Handa et al., described 47 cases between 1967 and 2007, noting that it was more prevalent in males, generally ipsilateral to the obstruction, and in most cases relieved by clearance of the obstruction.