URB597

URB597

Names
IUPAC name [3-(3-Carbamoylphenyl)phenyl] N-cyclohexylcarbamate
Identifiers
CAS Number	546141-08-6 N
3D model (Jmol)	Interactive image
ChemSpider	1156960 Y
ECHA InfoCard	100.164.994
IUPHAR/BPS	4339
MeSH	URB597
PubChem CID	1383884
InChI InChI=1S/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) Y Key: ROFVXGGUISEHAM-UHFFFAOYSA-N Y InChI=1/C20H22N2O3/c21-19(23)16-8-4-6-14(12-16)15-7-5-11-18(13-15)25-20(24)22-17-9-2-1-3-10-17/h4-8,11-13,17H,1-3,9-10H2,(H2,21,23)(H,22,24) Key: ROFVXGGUISEHAM-UHFFFAOYAO
SMILES O=C(NC1CCCCC1)OC2=CC=CC(C3=CC=CC(C(N)=O)=C3)=C2
Properties
Chemical formula	C20H22N2O3
Molar mass	338.41 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N  (what is YN ?)
Infobox references

URB597 (KDS-4103) is a relatively selective inhibitor of the enzyme fatty acid amide hydrolase (FAAH). FAAH is the primary degradatory enzyme for the endocannabinoid anandamide and, as such, inhibition of FAAH leads to an accumulation of anandamide in the CNS and periphery where it activates cannabinoid receptors. URB597 has been found to elevate anandamide levels and have activity against neuropathic pain in a mouse model.

URB597 was at one point being developed by Kadmus Pharmaceuticals, Inc. for clinical trials in humans.