U46619

U46619
Names

IUPAC name (Z)-7-[(1S,4R,5R,6S)-5-[(E,3S)-3-hydroxyoct-1-enyl]-3-oxabicyclo[2.2.1]heptan-6-yl]hept-5-enoic acid
Identifiers
CAS Number	56985-40-1^Y
3D model (JSmol)	Interactive image
ECHA InfoCard	100.164.944
IUPHAR/BPS	1888
PubChem CID	5311493
SMILES CCCCC[C@H](O)/C=C/[C@H]1[C@@H]2OC[C@@H](C2)[C@@H]1C/C=C\CCCC(O)=O
Properties
Chemical formula	C₂₁H₃₄O₄
Molar mass	350.49 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is ^YN ?)
Infobox references

U46619 is a stable synthetic analog of the endoperoxide prostaglandin PGH₂ first prepared in 1975, and acts as a thromboxane A₂ (TP) receptor agonist. It potently stimulates TP receptor-mediated, but not other prostaglandin receptor-mediated responses in various in vitro preparations. and exhibits many properties similar to thromboxane A₂, including shape change and aggregation of platelets and smooth muscle contraction. U46619 is a vasoconstrictor that mimics the hydroosmotic effect of vasopressin.

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