U.S. Route 64 in Oklahoma

U.S. Route 64
US-64 on a map of Oklahoma, highlighted in red
Route information
Maintained by ODOT
Length:	591.17 mi (951.40 km)
Existed:	November 11, 1926 – present
Major junctions
West end:	US 56 / US 64 / US 412 at the New Mexico state line
	I‑35 near Enid I‑44 in Tulsa I‑40 in Sallisaw and Roland
East end:	US 64 at the Arkansas state line
Highway system
United States Numbered Highway System List Special Divided Replaced Oklahoma State Highway System Interstate U.S. State Turnpikes ← SH-63 SH-65 →

I‑35 near Enid
I‑44 in Tulsa

U.S. Route 64 (US-64) is a U.S. highway running from the Four Corners area to the Outer Banks of North Carolina. Between these two points, the highway passes through the entire width of Oklahoma; a total of 591.17 miles (951.40 km) of US-64 lies in the state of Oklahoma. US-64 enters the state from New Mexico, crossing the line between the two states between Clayton, New Mexico, and Boise City in Cimarron County. The route runs the full length of the Oklahoma Panhandle, then serves the northernmost tier of counties in the main body of the state before dipping southeastward to Tulsa, the state's second-largest city. From Tulsa, the highway continues southeast, leaving Oklahoma just west of Fort Smith, Arkansas. In addition to Tulsa, US-64 serves fifteen Oklahoma counties and the cities of Guymon, Woodward, Enid, and Muskogee.