U.S. Route 21 Business (Beaufort, South Carolina)

U.S. Route 21
Highway system
United States Numbered Highway System List Special Divided Replaced

U.S. Route 21 Business
Location:	Beaufort, South Carolina
Length:	5.4 mi (8.7 km)
Existed:	1967–present

U.S. Route 21 Business
Location:	Orangeburg, South Carolina
Length:	2.9 mi (4.7 km)
Existed:	1967–present

U.S. Route 21 Connector
Location:	Orangeburg, South Carolina
Length:	1.5 mi (2.4 km)

U.S. Route 21 Connector
Location:	Columbia, South Carolina
Length:	2.9 mi (4.7 km)

U.S. Route 21 Business
Location:	Fort Mill, South Carolina
Length:	7.1 mi (11.4 km)
Existed:	1948–present

U.S. Route 21 Business
Location:	Jonesville-Elkin, North Carolina
Length:	7.8 mi (12.6 km)
Existed:	1966–present

U.S. Route 21 Business
Location:	Orangeburg, South Carolina
Length:	3.3 mi (5.3 km)
Existed:	1950–1967

U.S. Route 21 Business
Location:	Rock Hill, South Carolina
Length:	6.7 mi (10.8 km)
Existed:	1950–2013

U.S. Route 21 Bypass
Location:	Bluefield, West Virginia

Several special routes of U.S. Route 21 exist. In order from south to north they are as follows.

U.S. Route 21 Business (US 21 Bus) traverses through downtown Beaufort, via Sea Island Parkway, Carteret Street and Boundary Street.

U.S. Route 21 Connector (US 21 Conn) is an unsigned 1.5 miles (2.4 km) connector route from Broughton Street (US 178 Bus) to Chestnut Street (US 21/US 178), via Park Street and Columbia Road.

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