"Two Doors Down" is the second single from the Mystery Jets album Twenty One and it features a saxophone solo by Nik Carter (of The Blackjack Horns). The single became their second highest charting single in the UK Singles Chart, peaking at #24, second to "The Boy Who Ran Away" which charted one place higher at #23. In October 2011, NME placed it at number 100 on its list "150 Best Tracks of the Past 15 Years".

Musicomh gave a positive review saying that "With the help of Erol Alkan they convey this in sweeping, romantic gestures that wouldn't have been out of place in the charts in the 1980s - yet thanks to the producers's intervention sound bang up to date" and went on to say "With a melody that won't be leaving your brain for some time, this is one of the Jets' poppiest offering yet, given a dash of camp attitude to complete a memorable single".

Neumagazine gave the song 9 out of 10 stars. They said that it is "A homage to the 80s, rather than a piss-take, the light hearted synths and classic 'love story lyrics' make this a very fun track" and went on to say "It's the kind of nostalgia we actually like. The video is a rather enjoyable as well".

The tone of the song's promotional video is light-hearted with members of the band wearing 1980s-style clothing and dancing against fluorescent backdrops. Two female dancers also appear throughout the video.

This is the track listing for the single:

The song debuted in the UK Singles Chart at #87. After six weeks it had risen to #24, where it became their second highest charting song, as well as only their fourth UK Top 40 single. In total it spent 8 weeks in the chart, a record for the band.

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